Transgenic animals. New approaches to hypertension research.
نویسندگان
چکیده
منابع مشابه
Transgenic animals. New approaches to hypertension research.
We have shown that it is possible to generate transgenic rats efficiently, allowing direct experimentation in this species, without first testing constructs in the mouse. Having developed the technology for producing transgenic rats, we now hope to generate new and precise models of hypertension and to test candidate genes that may be responsible for the phenotype in existing animal models. The...
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The challenge in hypertension research is the elucidation of the primary genetic causes of elevated blood pressure. It is common knowledge that the basic information on how a cell, an organ, and the whole body function resides within the chromosomes and the individual genes, that is, their nucleotide DNA sequence. The problem with understanding primary (genetic) hypertension in humans is that s...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1991
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.17.3.394